Therapeutic compositions for bone repair

Patent Number: 9387250

Patent Date: 2016-07-12

Patent type: utility

Individuals having diabetes are more prone to fractures, periodontitis, and other bone related issues as compared to healthy individuals. Furthermore, bone healing in diabetic patients is prolonged. The invention provides a method for decreasing bone resorption or increasing bone formation or promoting bone healing in diabetic patients. In particular, a biodegradeable polymer, such as a polyanhydride salicylate is administered at or near a bone defect site, and upon hydrolysis of the polymer will releases biologically active salicylic acid.

Inventors

First Name Last Name City State Country
Kathryn E. Uhrich - - -
Roselin Rosario-Meléndez - - -
Dana Graves - - -
Keisuke Wada - - -
Joseph P. Fiorellini - - -
Michelle Morano - - -
Sabrina Sachiko Snyder - - -

IPCs

Section Class Sub Class Group Sub Group
A 61 P 19 08
A 61 K 31 60
A 61 K 31 192
A 61 K 45 06
A 61 L 27 58
A 61 K 33 00
A 61 L 29 16
A 61 K 47 48

Assignee

Organization First Name Last Name City State Country
The Trustees of the University of Pennsylvania - - - - -
Rutgers, The State University of New Jersey - - - - -