Agent for evading immune response

Patent Number: 9387175

Patent Date: 2016-07-12

Patent type: utility

It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.

Inventors

First Name Last Name City State Country
Toru Takahashi - - -
Keietsu Abe - - -
Kazuyoshi Kawakami - - -
Tadafumi Ajiri - - -
Manabu Fukumoto - - -
Seiichi Takami - - -
Takanari Togashi - - -
Kimihide Muragaki - - -

IPCs

Section Class Sub Class Group Sub Group
A 61 K 38 16
A 61 K 9 16
C 01 G 49 08
C 09 C 1 24
A 61 K 49 18
B 82 Y 5 00
B 82 Y 40 00
B 22 F 1 00
B 82 Y 30 00

Assignee

Organization First Name Last Name City State Country
Tohoku University - - - - -