Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies

Patent Number: 9387216

Patent Date: 2016-07-12

Patent type: utility

Described herein are methods and compositions for the treatment of prostate cancer in a subject in need thereof. The prostate cancer may be a castration resistant and an androgen receptor antagonist-resistant prostate cancer. The methods may comprise administering to the subject a CYP17-lyase inhibitor of Formula II.

Inventors

First Name Last Name City State Country
Vincent O. Njar - - -
Douglas B. Jacoby - - -
Karen J. Ferrante - - -
Amina Zoubeidi - - -
Eva Corey - - -

IPCs

Section Class Sub Class Group Sub Group
A 61 K 31 58
C 07 J 43 00
C 12 Q 1 68

Assignee

Organization First Name Last Name City State Country
University of Washington - - - - -
University of Maryland, Baltimore - - - - -
Thallion Pharmaceuticals Inc. - - - - -