ANTIBODIES CONTAINING ENHANCED SIGNAL

Brand	Owner	Address	Description
AMPIFLOW	ENZO LIFE SCIENCES, INC.	Suite 3 81 Executive Blvd Farmingdale NY 11735	Antibodies containing an enhanced signal detection system based on branched DNA complexes for research use;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

The present invention features antibodies and antibody fragments that specifically bind a CD4-inducible HIV gp120 epitope that is enhanced by binding a co-receptor for HIV, such as CCR5 or CXCR4, and pharmaceutical compositions comprising the antibodies or antibody fragments. The invention also features nucleic acids encoding the antibodies or antibody fragments, pharmaceutical compositions comprising the nucleic acids encoding the antibodies or antibody fragments, vectors comprising the nucleic acids, and cells comprising the vectors. The invention further features methods of identifying antibodies or antibody fragments with broadly neutralizing activity against HIV. The invention also features methods of inhibiting HIV entry into cells and methods of inhibiting replication of HIV in mammals, using the antibodies and nucleic acids of the invention.