APPLE EXTRACT USE

Brand	Owner	Address	Description
APPLEPHENON	NIKKA WHISKY DISTILLING CO., LTD., THE	4-31, Minami-Aoyama 5-chome Minato-ku Tokyo Japan	apple extract for use in the food and beverage industry;apple extract for use in the pharmaceutical, veterinary and sanitary industry;apple extract for use in the cosmetic and toiletry industry;apple extract for use as an ingredient in the manufacture of foods, beverages, cosmetics, toiletries, pharmaceuticals, pet foods, animal feeds, veterinary preparations, personal hygiene preparations and household sanitary preparations;apple extract for use in the pet food and animal feed industry;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

Hypericin has been shown to specifically inhibited T-type calcium channel activity. Hypericum extract containing hypericin also inhibited T-type calcium channel activity. Moreover, other chemicals in Hypericum extract showed a synergistic effect to hypericin. In view of this, hypericin or hypericin-containing Hypericum extract can be used as T-channel blockers. Hypericum extract, extract of other species of the Hypericum genus, extract of other plants containing hypericin, hypericin, hypericin derivatives, hypericin analogs, such as pseudohypericin, and other hypericum extract constituents can be used as therapeutics targeted at T-type calcium channels for treatment of diseases associated with T-channel abnormality. Methods for administering hypericin and hypericum extract are disclosed.