HUMAN DERIVED BIOLOGICAL MATERIALS

Brand	Owner	Address	Description
ENTICE	RTI SURGICAL, INC.	11621 Research Circle Alachua IL 32615	Human derived biological materials, namely, implants for use with orthopedic and bone restoration and reconstruction procedures, none of the foregoing including bone-cutting instruments;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

Methods for treating medical conditions induced by interleukin-4 involve administering an IL-4 antagonist to a patient afflicted with such a condition. Suitable IL-4 antagonists include, but are not limited to, IL-4 receptors (such as a soluble human IL-4 receptor), antibodies that bind IL-4, antibodies that bind IL-4R, IL-4 muteins that bind to IL-4R but do not induce a biological response, molecules that inhibit IL-4-induced signal transduction, and other compounds that inhibit a biological effect that results from the binding of IL-4 to a cell surface IL-4R. Particular antibodies provided herein include human monoclonal antibodies generated by procedures involving immunization of transgenic mice. Such human antibodies may be raised against human IL-4 receptor. Certain of the antibodies inhibit both IL-4-induced and IL-13-induced biological activities.