HUMAN ENGINEERING

Brand	Owner (click to sort)	Address	Description
HUMANEERING	Humaneering International, Inc.	601 Loran Pointe Circle Seneca SC 29672	HUMAN ENGINEERING;conducting motivational programs to increase employee productivity;
SPECTRACOM HUMAN ENGINEERING	SPECTRACOM TECHNOLOGIES CORPORATION	14700 N. Hayden Scottsdale AZ 85260	HUMAN ENGINEERING;Consulting services in the field of ergonomics;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

It has been discovered that there are at least two significant antigens present on the cells of animal species such as pigs that elicit an immune or inflammatory response immediately upon implantation into humans or contact with human serum. The first is an ?-galactosyl (Gal) epitope, for example, Gal?(1->3)Gal?(1->4)GlcNac (linear B type 2) or Gal?(1->3) Gal?(1->4)Glc (linear B type 6). The second is an N-glycolylneuraminic acid (NeuGc) structure. By eliminating these epitopes, preferably by genetically engineering the animal so that the epitope is either not produced or is greatly reduced, or by chemical or enzymatic treatment of the animal's cells to remove the epitopes, it is possible to produce organs, tissues and cells suitable for xenotransplantation into humans. Cells can be rendered even more compatible by genetically engineering the animal to express a human complement regulatory protein (inhibitor), such as CD59, on its cells, or to express an excess of a pig complement regulatory protein.