MULTI AMINO ACIDS FOR PHARMACEUTICAL USE

Brand	Owner	Address	Description
AMINA-21	MILLER PHARMACAL GROUP, INC.	350 RANDY ROAD, SUITE 2 CAROL STREAM IL 60188	MULTI-AMINO ACIDS FOR PHARMACEUTICAL USE;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

The present invention relates to an NST500 compound of general formula (I): comprising the following components: X1-X2-{(X3)a/X4/X5}-X6, wherein: X1 stands for a saturated or unsaturated fatty acid residue comprising 6-20 carbon atoms; or a cysteine residue bound through a thioether bond to a prenyl group comprising 5-20 carbon atoms; said residue being linked to the adjacent component of the compound through an amide bond; X2 is 0; X3 comprises 1-6 amino acids, of which 1-6 are positively charged and 0-2 are negatively charged, the other amino acid residues being polar uncharged amino acids; X4 comprises 1-6 amino acids, of which 1-2 are aromatic amino acids, the other amino acids being selected among polar uncharged amino acids and hydrophobic aliphatic amino acids; X5 comprises 6-8 amino acids, of which 4-6 are positively charged and 0-2 are negatively charged, the other amino acid residues being polar uncharged amino acids, wherein the amino acids form a cyclic structure; X6 is a compound of general formula II, wherein Z stands for a spacer group selected among alkane and alkene containing 1-5 carbon atoms, J stands for a functional group selected among amines, thiols, alcohols, carboxylic acids and esters, aldehydes and alkyl halides; U is 0 or is selected among a labeling group; wherein a stands for an integer of 1-3; and the groups X3, X4 and X5 being located at various places in the compound; as well as functional equivalents thereof and/or compounds having the same biological activity thereto. The present also relates to pharmaceutical compositions and methods of using the same.