NONRADIOACTIVE CHEMICALLY MODIFIED NUCLEOTIDES

Brand	Owner	Address	Description
BIO-PROBE	Enzo Biochem, Inc.	Suite 3 81 Executive Blvd Farmingdale NY 11735	NONRADIOACTIVE CHEMICALLY MODIFIED NUCLEOTIDES AND POLYNUCLEOTIDES FOR THE DETECTION OF SPECIFIC GENETIC MATERIALS, FOR IN VITRO RESEARCH AND DIAGNOSTIC USE;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

A random combinatorial selection method is disclosed for the construction of oligonucleotide aptamers in which nuclease resistance is conferred by the inclusion of modified nucleotides. The modified nucleotides are incorporated during PCR amplification to form achiral modified oligonucleotides. Thio-substituted aptamers are provided that bind tightly to the nuclear factor for human IL6 (NF-IL6).