NUCLEIC ACID LIBRARY PREPARATION KITS

Brand Owner Address Description
AMPINEXT ENZO LIFE SCIENCES, INC. Suite 3 81 Executive Blvd Farmingdale NY 11735 Nucleic acid library preparation kits comprised of buffers, adaptors, beads, primers, enzymes and columns for construction and preparation of nucleic acid libraries for next generation sequencing applications;
 

Where the owner name is not linked, that owner no longer owns the brand

   
Technical Examples
  1. An expression library comprising a repertoire of nucleic acid sequences cloned from a non-immunised source, each nucleic acid sequence encoding at least part of a variable domain of a heavy chain derived from an immunoglobulin naturally devoid of light chains (VHH) wherein the extent of sequence variability in the library is enhanced compared to the corresponding naïve expression library by introducing mutations in one or more of the complementarity determining regions (CDRs) of the nucleic acid sequences or by generating alternative combinations of CDR and framework sequences not naturally present in the naïve library repertoire. Also disclosed is the use of such a library in preparing antibodies, more particularly antibody fragments.