SYNTHETIC SUBSTANCES FOR USE AS

Brand	Owner	Address	Description
PALACOS	HERAEUS MEDICAL GMBH	Philipp-Reis-Strasse 8/13 61273 Wehrheim Germany	SYNTHETIC SUBSTANCES FOR USE AS JOINING MEANS FOR NATURAL BONES AND BONE SUBSTITUTES, PROTHESIS IN AND ON THE HUMAN BODY, [ FILLING MATERIAL FOR TOOTHROOTS FOR DENTAL PURPOSES, SYNTHETIC SUBSTANCES FOR EMBEDDING BONES AND CARTILAGES AS VELL AS FOR SPLINTING BONES, BONE SUBSTITUTES AND BONE FRACTURES AND FOR THE PRODUCTION OF ORTHOPAEDIC, MEDICAL AND SURGICAL BANDAGES ];
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

(Beauveria) sp. FO-6979 (FERM BP-6681), which belongs to the genus Beauveria and is capable of producing FO-6979-M0, -M1, -M2, -M3 and -M4 substances, is cultured in a medium to thereby accumulate the FO-6979-M0, -M1, -M2, -M3 and -M4 substances in the liquid culture medium. Then the FO-6979-M0, -M1, -M2, -M3 and -M4 substances are collected from the culture medium. The substances thus obtained are less toxic, specifically inhibit acyl-Coenzyme A: cholesterol acyltransferase, and inhibit the formation of oil droplets in macrophages. Owing to these characteristics, the above substances are useful in preventing and treating human diseases caused by cholesterol accumulation.