TWELVE PLUS

Brand	Owner (click to sort)	Address	Description
TWELVEPLUS	GFK US MRI	200 LIBERTY ST. 4TH FLOOR NEW YORK NY 10281	TWELVE PLUS;market research services through the use of a computer database and reports;
TWELVEPLUS	MEDIAMARK RESERACH INC.	75 Ninth Avenue 5th Floor New York NY 10011	TWELVE PLUS;market research services through the use of a computer database and reports;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

The present invention is directed to a method to prevent or reduce postoperative corneal subepithelial haze after excimer laser photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK) surgery. According to the method, a therapeutically effective amount of one or more plasminogen activators, most preferably urokinase (uPA), is administered topically to the surface of the affected eye at levels between 0.1 and 2,500 IU/ml, about eight to twelve times on the day of surgery, and four to eight times per day for about the next six to twelve days thereafter. The most preferred therapeutic amount is from about 0.1-1 IU uPA/ml, and also 1-10 IU/ml. Plasminogen activators that can be used in the inventions include urokinase, prourokinase, streptokinase and mutants thereof. The invention also covers topical ophthalmic compositions that include one or more plasminogen activators, most preferably uPA, to prevent or reduce postoperative corneal subepithelial haze.