Simulations Plus, Inc.

AB-BREVIATE!

computer software that speeds data entry of difficult or repetitive words, phrases or paragraphs across software applications by allowing users to define, and substitute, one set of key strokes for another;

CARDIOSYM

Computer software, namely, downloadable computer software for conducting simulations of compounds such as drugs or chemicals to evaluate and model their effects on the cardiovascular system, including the heart;CARDIO SYM;

COGNIGEN

In the statement, column 1, before line 1, Cognigen Corporation (New York Corporation), 395 Youngs Road, Williamsville, NY 14221, by change of name should be inserted.;ELECTRONIC STORAGE OF DATA;BUSINESS MARKETING CONSULTING SERVICES FOR PHARMACEUTICAL AND HEALTHCARE INDUSTRIES;PHARMACEUTICAL RESEARCH IN THE FIELDS OF PHARMACOKINETICS, PHARMACODYNAMICS, PHARMACEUTICAL ECONOMICS, AND PHARMACEUTICAL OUTCOMES;

DILISYM

Scientific research and consultations services in the field of research and development of drugs or chemicals for others, including conducting simulations of drug-liver interactions, and designing computer software for others to use in modeling liver responses to a drug or chemical;

DILISYM

Computer software, namely, computer software for modeling liver response to a drug or chemical; computer software for conducting simulations of drug-liver interactions; computer software for predicting pharmacokinetic, pharmacodynamic, and liver responses to a drug or chemical;

DRUGPHARMER

Computer software for data analysis and interpretation in the field of automated drug discovery;DRUG PHARMER;research and development for others and providing information to others in the field of automated drug discovery;

FUTURELAB

educational software that enables users to conduct simulated science experiments on a computer;FUTURE LABORATORY;

GASTROPLUS

Computer software that predicts the percent of intestinal absorption of an orally administered drug;GASTRO PLUS;

GPX

downloadable computer software, namely, computer software for modeling and the conducting of simulations of properties of drugs or chemicals including absorption, release rate, bioavailability, pharmacokinetics, and pharmacodynamics; downloadable computer software which allows for prediction of drug-to-drug interactions; downloadable computer software for the prediction of drug effects on animals and virtual patient populations; downloadable computer software which allows researchers to adjust pharmacodynamic models to observed data and to then use the resulting fitted models to predict pharmacodynamic changes due to changes in dose, dosage form, and dosing regimen of a drug or chemical; downloadable computer software which allows for the generation of in vitro-in vivo correlations; downloadable computer software which allows for the prediction of absorption and systemic distribution/ elimination for large molecules;

HELIXGEN

Computer software that calculates a three-dimensional model of the transmembrane spanning helical domains of a protein or receptor from a primary amino acid sequence;HELIX GENERATION;

ILDSYM

Computer software, namely, downloadable computer software for conducting simulations of compounds such as drugs or chemicals to evaluate and model their effects on lung disease, namely, interstitial lung disease;

IPFSYM

Computer software, namely, downloadable computer software for conducting simulations of compounds such as drugs or chemicals to evaluate and model their effects on the respiratory system, including the lungs;IPF SYM;

LEADPHARMER

COMPUTER SOFTWARE FOR DATA ANALYSIS AND INTERPRETATION IN THE FIELD OF AUTOMATED DRUG DISCOVERY;LEAD PHARMA;research and development for others and providing information to others in the field of automated drug discovery;

MITOSYM

Computer software, namely, computer software for modeling cellular response to a drug or chemical for use in the fields of pharmaceutical, medical, or preclinical research; computer software for conducting simulations of cellular bioenergetics in response to a drug or chemical for use in the fields of pharmaceutical, medical, or preclinical research; computer software for predicting cellular bioenergetics response to a drug or chemical for use in the fields of pharmaceutical, medical, or preclinical research;

NAFLDSYM

Scientific research and consultations services in the fields of research and development of compounds such as drugs or chemicals for others, including conducting simulations of compounds to evaluate and model their effects on non-alcoholic fatty liver disease (NAFLD);

NAFLDSYM

Computer software, namely, downloadable computer software for conducting simulations of compounds such as drugs or chemicals to evaluate and model their effects on liver disease, namely, non-alcoholic steatohepatitis or non-alcoholic fatty liver disease;NAFLD SYM;

QMPRPLUS

Computer software that facilitates the study of Quantitative Molecular Permeability Relationships (QMPR) by translating a Simplified Molecular Input Line Entry Specification (SMILES) representation of a drug molecule into molecular descriptors that are used to predict cellular permeability;QMPR PLUS;

RADASYM

Computer software, namely, downloadable computer software for conducting simulations of compounds such as drugs or chemicals to evaluate and model their effects on radiation exposure;RADA SYM;

RENASYM

Computer software, namely, downloadable computer software for modeling kidney response to a drug or chemical; downloadable computer software for conducting simulations of kidney interactions with a drug or chemical; downloadable computer software for predicting pharmacokinetic, pharmacodynamic, and kidney responses to a drug or chemical;

SIMPOPS

Computer software for use in the fields of biomedical research and healthcare, namely, customizable software designed for use by biopharmaceutical companies to simulate individuals with variability in one or more patient characteristics such as drug metabolism, drug distribution, and drug effects, in developing a simulated patient population for the purpose of predicting and recommending options available for drug development based on outcomes observed from the simulated patients and simulated patient population;

SIMULATIONS PLUS

educational and pharmaceutical software;